Open source caching proxy servers

Datacenter Diagram
Hello lazy web, I’m looking for some advice on caching proxy servers and thought you might have some good pointers!

We currently front our site with 3 caching proxy servers to offload static content from the web servers and we haven’t found the right solution yet. We’ve tried a number of solutions including Oops and Apache with mod_cache (which we’re currently running) but they are either missing a critical feature, have buggy caching behavior, or crash under heavy load. The main features I’m looking for are:

1. Caches static content and pages and respects the expires header
2. Can gzip content on the fly (this saves us a bundle in bandwidth costs)
3. Can easily clear the cache when we move a new release live

I’d prefer an open-source product but if we end up needing to go with a commercial solution as a last resort I’m open to that as well, thanks for your suggestions or help!

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